Approximately one year after successful treatment with cytotoxic chemotherapy and radiotherapy, patients with advanced Small Cell Lung Cancer (SCLC), which primarily affects heavy smokers, generally relapse with recurrence of tumours that are resistant to further chemotherapy. At this point, the affected patients usually only have a few months to live. The reason for this was hitherto unknown. Researchers at MedUni Vienna, led by Gerhard Hamilton (Department of Surgery), have now discovered that circulating tumour cells combine, making previously chemo-sensitive cells into chemo-resistant cell complexes.
Children in Power – in the words of the all-time hit by Herbert Grönemeyer, it is the kids who are "ruling" for a week at the Medical University of Vienna. Today MedUni Vienna's Vice Rector for Clinical Matters, Oswald Wagner, opened KinderuniMedizin [Children’s University - Medicine], which is celebrating its 15th anniversary this year and offering a total of 6,000 student places in 87 classes focusing on the theme of "Saving lives, helping people". The opening lecture entitled "What exactly is epilepsy?" was given by Helmut Kubista from MedUni Vienna's Division of Neurophysiology and Neuropharmacology
Some newly born piglets shiver even when they are kept warm. So-called “shaking piglets” have symptoms that resemble those of the classical swine fever, with extensive damage to the brain and the spinal cord. The viral origin of the disease was clarified only recently with the discovery in Europe and the USA of an atypical porcine pestivirus. Researchers at the Vetmeduni Vienna have now discovered a further new virus in shaking piglets on an Austrian farm. The pathogenic agent is related to the Australian Bungowannah virus and more distantly to the classical swine fewer virus. Because of the symptoms it causes, the new virus is termed LINDA virus (Lateral shaking Inducing NeuroDegenerative Agent). Its discovery was recently announced in the journal “Emerging infectious diseases”.
This is a momentous day for any startup, but for a team on a mission it’s even greater. Today we’re proud to announce that we’re joining the Roche family to help create an open digital diabetes ecosystem that revolves entirely around people with diabetes.
A single-gene mutation may cause a severe bowel disease in children. This could be shown in a recent study by an international research team led by Kaan Boztug at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD) together with Michael Lenardo, National Institute of Health (NIH), Bethesda. The newly discovered alterations lead to total loss of a protein called CD55, causing life-threatening bowel inflammation, chronic diarrhea and vascular thrombosis. The researchers unraveled the underlying molecular mechanisms and discovered previously unknown regulatory pathways relevant to bowel homeostasis. As a consequence of their findings, the researchers could identify a clinically approved drug which may specifically interfere with aberrant signaling involved in this previously unknown disease. The manuscript has now been published in the renowned New England Journal of Medicine.